Michael addition of pyrimidine and purine nucleobases to substituted as well as unsubstituted α,β-unsaturated esters efficiently proceeds in the presence of catalytic amount of zinc oxide in ionic liquid 1-butyl-3-methylimidazolium bromide (ZnO/[bmim]Br) under microwave irradiation to afford carboacyclic nucleosides, as biologically important compounds, in good to excellent yields and in short reaction times.
The ionic liquid, N,N,N,N-tetramethylguanidiniumtriflate (TMGTf) was found to be an efficient catalyst solvent for Henry reaction between nitromethane and isatin derivatives to provide 3-hydroxy-3-(nitromethyl)indolin-2-one under mild conditions. The ionic liquid amenable to successive recycling without appreciable decrease in activity. Synthesized compounds have been screened for their anti-diabetic activity.(The ionic liquid, N,N,N,N-tetramethylguanidiniumtriflate (TMGTf) was found to […]
Succinimidinium hydrogensulfate ([H-Suc]HSO4), as a new and stable derivative of succinimide, is easily prepared by the reaction of succinimide with neat sulfuric acid. This ionic liquid can be used as an efficient catalyst for the acetylation of alcohols, phenols, thiols and amines at room temperature under mild and solvent free conditions. All the products are […]
In this research, a green, operationally simple, highly efficient and facile cascade Biginelli reaction using various aromatic aldehydes, ethyl acetoacetate, and urea/thiourea has been developed. First, the ionic liquid was prepared from the reaction of 1-methyl-2-pyrolidone with methane sulfonic acid. Then, this ionic liquid was applied as an acidic catalyst in the synthesis of dihydropyrimidinones […]
In this research, various polycyclic fused acridines were synthesized via the highly efficient and green one-step four-component reaction between isatins, dimedone, various amines, and dimethylacetylenedicarboxylates (DMAD/DEAD) in the presence of n-octyl-3-methylpipyridinium bromide ([OMePPy]+Br–) as a newly prepared ionic liquid, in absolute green situations at room temperature under solvent-free conditions. The ionic liquid characterized by 1H […]
This review papers aims to comprehensively address the various aspects of ionic liquids and supported ionic liquids, which constitute a significant branch within the expansive field of green catalyst. Specifically, it delves into the recent advancements made in this domain over the past three years for the synthesis of heterocyclic compounds. In the introduction section […]
In this research, we develop and prepare some of the polymers based on polythioesters using cetrimide as an ionic liquid and phase transfer catalyst. All of the polymers were prepared through the reaction of 5,5′-methylenebis (1,3,4-oxadiazole-2-thiol) with five types of diacyl chloride derivatives in the presence of cetrimide as phase transfer catalyst in the mixture […]
Pyrimido[4,5-b]quinolones play a significant role in medicinal chemistry owing to their various biological properties, including antihistaminic, antimalarial, antifungal, anticancer, antioxidant, antiviral, anti-microbial, and anti-inflammatory activities. A dual acidic ionic liquid anchored on graphene oxide nanosheets (GO-Si-Pr-Lysin-SO3H) was provided and characterized using transmission electron microscopy (TEM), scanning electron microscopy (SEM), X-ray diffraction (XRD), thermogravimetric analysis (TGA), […]
