Cu-catalysis was employed to create numerous (E)-5-bromo-N-aryl oxindole nitrones with satisfactory to excellent coupling efficiencies. This process involved the reaction of N-unprotected 5-bromoisatin-3-oximes and aryl-boronic acid derivatives under mild reactive conditions. Remarkably, the reaction exhibited tolerance towards several aryl-boronic acids containing diverse functional sensitivity subgroups (73% to 97% yields and 2 to 6 h). Extensive […]
Cu-catalysis was employed to create numerous (E)-5-bromo-N-aryl oxindole nitrones with satisfactory to excellent coupling efficiencies. This process involved the reaction of N-unprotected 5-bromoisatin-3-oximes and aryl-boronic acid derivatives under mild reactive conditions. Remarkably, the reaction exhibited tolerance towards several aryl-boronic acids containing diverse functional sensitivity subgroups (73% to 97% yields and 2 to 6 h). Extensive […]
Ammonium monovanadate (NH4VO3) has been devoted as an efficient, commercially available, eco-friendly and reusable catalyst for the synthesis of bis(indolyl)methanes (BIMs), oxindole derivatives and also Michael adducts of indoles at 50 °C under solvent-free conditions. The reusability of this solid acid catalyst in addition with its selectivity has also been examined.
The ionic liquid, N,N,N,N-tetramethylguanidiniumtriflate (TMGTf) was found to be an efficient catalyst solvent for Henry reaction between nitromethane and isatin derivatives to provide 3-hydroxy-3-(nitromethyl)indolin-2-one under mild conditions. The ionic liquid amenable to successive recycling without appreciable decrease in activity. Synthesized compounds have been screened for their anti-diabetic activity.(The ionic liquid, N,N,N,N-tetramethylguanidiniumtriflate (TMGTf) was found to […]
In this study, novel CuO/g-C3N4 nanocomposite was simply synthesized by impregnation of g-C3N4 with CuO nanoparticles. Then, the heterogeneous catalyst was characterized by various techniques including Fourier transform infrared spectroscopy (FT-IR), X-ray diffraction (XRD), thermogravimetric analysis (TGA) and transmission electron microscopy (TEM). Moreover, the Friedel–Crafts 3-indolylation reaction of isatin with indole derivatives in water as […]
The preparation, characterization, and immobilization of cobalt (III) salen complex on CoFe2O4@SiO2 nanoparticle (CoFe2O4@SiO2@ Co(III) salen complex) are described. Co(III) salen complex loaded on ferrite cobalt-silica nanoparticle is characterized by TEM, SEM-EDX, VSM and FT-IR analyses. The efficiency of CoFe2O4@SiO2@Co(III) salen complex as a catalyst was carried out in the 3-indolylation reaction of indole with […]
In this research, various polycyclic fused acridines were synthesized via the highly efficient and green one-step four-component reaction between isatins, dimedone, various amines, and dimethylacetylenedicarboxylates (DMAD/DEAD) in the presence of n-octyl-3-methylpipyridinium bromide ([OMePPy]+Br–) as a newly prepared ionic liquid, in absolute green situations at room temperature under solvent-free conditions. The ionic liquid characterized by 1H […]
