To be fairly general and catalyst is easily separated by magnetic devices and can be reused without any apparent loss of activity for the reaction. Fe3O4 nanoparticles were prepared by chemical coprecipitation method and was found to be a mild and effective catalyst for the efficient, one-pot, three-component synthesis of 2,4,5-trisubstituted imidazoles at room temperature […]
A simple highly versatile and efficient sonochemical synthesis of 1,2,4,5-tetrasubstituted and 2,4,5-trisubstituted imidazoles is achieved by condensation of 1,2-dicarbonyl compound, aldehyde, ammonium acetate and primary amine using antimony trichloride immobilized on silica gel (SiO2-OSbCl2) as a catalyst in ethanol at moderate temperature. Operational simplicity, practicability and applicability to various substrates make this method an interesting […]
