Magnetic Fe3O4 nanoparticles as a highly efficient catalyst for the synthesis of imidazoles under ultrasound irradiation

Authors

• Javad Safari ¹
• Zohre Zarnegar ²

1. Laboratory of Organic Compound Research, Department of Organic Chemistry, College of Chemistry, University of Kashan, P.O. Box: 87317-51167 Kashan, I.R. Iran.
2. Laboratory of Organic Compound Research, Department of Organic Chemistry, College of Chemistry, University of Kashan, P.O. Box: 87317-51167, Kashan, I.R., Iran.

Abstract

To be fairly general and catalyst is easily separated by magnetic devices and can be reused without any apparent loss of activity for the reaction. Fe3O4 nanoparticles were prepared by chemical coprecipitation method and was found to be a mild and effective catalyst for the efficient, one-pot, three-component synthesis of 2,4,5-trisubstituted imidazoles at room temperature under ultrasound irradiation. The high yields of products and short reaction time were attributed to the nanosize of about 20 nm in which the catalyst could act as a nanoreactor. This methodology is found.

Keywords

• imidazole
• ultrasound irradiation
• Heterogeneous catalyst
• Fe3O4 nanoparticles