Sulfuric acid {[3-(3-silicapropyl)sulfanyl]propyl}ester as a recyclable solid acid catalyst for the synthesis of α-amino nitriles

Authors

• Somayeh Ghasemi ¹
• Mojtaba Baghernejad ²
• Khodabakhsh Niknam ³

1. Department of Chemistry, Gachsaran Branch, Islamic Azad University, Gachsaran, Iran.
2. Young and Reasearcers Elite, Gachsaran Branch, Islamic Azad University, Gachsaran, Iran
3. Department of Chemistry, Faculty of Sciences, Persian Gulf University, Bushehr 75169, Iran.

Abstract

Sulfuric acid {[3-(3-silicapropyl)sulfanyl]propyl}ester (SASPSPE) is employed as a recyclable catalyst for the synthesis of α-amino nitriles. These syntheses were performed via a one-pot three-component condensation of aldehydes, amines, and trimethylsilyl cyanide under mild reaction conditions at room temperature. The catalyst could be recycled and reused several times without any loss of efficiency.

Keywords

• Aldehydes
• Sulfuric acid ([3-(3-silicapropyl)sulfanyl]propyl)ester
• α-Amino nitriles
• Amines
• Catalyst
• Synthesis