Silica-bonded n-propyltriethylene-tetramine as a recyclable solid base catalyst for the synthesis of 2-amino-5-oxo-5,6,7,8-tetrahydro-4H-chromenes

Authors

• Marzieh Makvandi ¹
• Fatemeh Abiar Dil ¹
• Ameneh Malekzadeh ¹
• Mojtaba Baghernejad ²
• Khodabakhsh Niknam ³

1. Department of Chemistry, Gachsaran Branch, Islamic Azad University, Gachsaran, Iran.
2. Young and Reasearcers Elite, Gachsaran Branch, Islamic Azad University, Gachsaran, Iran
3. Department of Chemistry, Faculty of Sciences, Persian Gulf University, Bushehr 75169, Iran.

Abstract

Silica-bonded n-propyltriethylene-tetramine (SBNPTT) was found as an efficient solid base for the synthesis of 2-amino-5-oxo-5,6,7,8-tetrahydro-4H-chromenes. Chromene derivatives were obtained via the three-component condensation reaction of aromatic aldehydes, malononitrile, and dimedone at 80 oC under solvent-free conditions. The heterogeneous solid base showed much the same efficiency when used in consecutive reaction runs.

Keywords

• Catalyst
• Synthesis
• Chromenes
• Silica-bonded n-propyltriethylene-tetramine
• Solid bases