A green, efficient, and rapid procedure for the synthesis of pyrano[3,2-c] quinoline and pyrano[3,2-c]pyridone derivatives catalyzed by [BMIm]Cl

Authors

• Esmayeel Abbaspour-Gilandeh ¹
• Seyyedeh Cobra Azimi ²
• Kurosh Rad-Moghadam ³
• Aidin Mohammadi-Barkchai ⁴

1. Young Researchers and Elites Club, Ardabil Branch, Islamic Azad University, Ardabil, Iran.
2. Young Researchers and Elites Club, Rasht Branch, Islamic Azad University, Rasht, Iran.
3. Chemistry Department, University of Guilan, P.O. Box 41335-19141, Rasht, Iran.
4. Department of Applied Chemistry, Ardabil Branch, Islamic Azad University, Ardabil, 56157, I.R. Iran.

Abstract

A highly practical and efficient preparation of pyrano[3,2-c]pyridone and pyrano[3,2-c]quinoline derivatives was developed via an ionic liquid mediated and promoted multi-component reaction of malononitrile, aldehyde, and 4-hydroxyquinolin-2(1H)-one or 4-hydroxy-6-methylpyridin-2(1H)-one. The combinatorial syntheses were achieved for the first time without applying extra activation energy at ambient temperature while making use of [BMIm]Cl as a catalyst solvent.

Keywords

• Catalyst
• Ionic liquid
• Aldehydes
• 3-dicarbonyl compounds