The ionic liquid Li(OHCH2CH2NH2)(CF3OAC) was found to efficiently catalyze the three-component reaction between different enols, aldehydes, and malononitrile , leading to rapid synthesis of 2-amino-4H-chromene derivatives in fairly high yields. The catalyst is easily prepared, highly stable, simple to handle and recycled for several times without significant loss of activity. The method is simple, starts […]
Sucrose is applied as an efficient catalyst for the three-component reaction consisting of aromatic aldehydes, malononitrile and resorcinol in a mixture of water and ethanol media as green solvents. The advantages of this method are excellent yeild, inexpensive catalyst and more environmentally friendly. Mechanistic insight into the synthesis of 2-amino-4H-chromene included spectral kinetics approaches is […]
