Catalytic activity of AlHMS was investigated as a cheap heterogeneous reusable catalyst in some multi-component reactions for the synthesis of various chromenes. Three-component reaction of 2-hydroxy-naphtoquinone with an aromatic aldehyde and dimedone or barbituric acid in H2O under reflux conditions was performed using AlHMS in relatively good yields. The approach was more extended using psuedo […]
In the present study, robust, versatile and straightforward strategy for the diversity-oriented convergent synthesis of a vast range of highly functionalized and biologically effective chromenes is introduced with the reaction of malononitrile, dimedone/cyclohexadione/4-hydroxycoumarin and benzaldehydes in the presence of [γ-Fe2O3@HAp-Si(CH2)3BF4@DMIM] as the catalyst. The structures of all the newly synthesized products were characterized by spectroscopic […]
