1,3-Dichloro-5,5-dimethylhydantoin: an efficient catalyst for the solvent free synthesis of 1,8-dioxo-octahydro-xanthenes

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  • Farhad Shirini1,
  • Kurosh Rad-Moghadam2,
  • Tahereh Naghdi3,
  1. Department of Chemistry, College of Science, University of Guilan, Rasht, Iran
  2. Chemistry Department, University of Guilan, P.O. Box 41335-19141, Rasht, Iran.
  3. Department of Chemistry, College of Science, University of Guilan, Rasht, zip code 41335, I.R. Iran

Published in Issue 2024-02-03

How to Cite

Shirini, F., Rad-Moghadam, K., & Naghdi, T. (2024). 1,3-Dichloro-5,5-dimethylhydantoin: an efficient catalyst for the solvent free synthesis of 1,8-dioxo-octahydro-xanthenes. Iranian Journal of Catalysis, 2(2). https://oiccpress.com/ijc/article/view/3723

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Abstract

This paper describes the applicability of 1,3-dichloro-5,5-dimethylhydantoin, as a cheap, stable and commercially available catalyst, in the promotion of the synthesis of 1,8-dioxo-octahydro-xanthenes (DOXOs) via the one-pot condensation of aldehydes and cyclic 1,3-dicarbonyl compounds. This novel synthetic method has the advantages of high yields, short reaction times, low cost and availability of the catalyst, solvent-free reaction conditions, simplicity and easy work-up compared to the conventional methods reported in the literature.

Keywords

  • 3-dicarbonyl compounds,
  • 3-Dichloro-5,
  • 5-dimethylhydantoin. Cyclic 1,
  • 8-Dioxo-octahydro-xanthenes,
  • Aldehydes
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