OICC Press Iranian Journal of Catalysis 2345-4865 2 2 2024 02 03 1,3-Dichloro-5,5-dimethylhydantoin: an efficient catalyst for the solvent free synthesis of 1,8-dioxo-octahydro-xanthenes EN Farhad Shirini Department of Chemistry, College of Science, University of Guilan, Rasht, Iran 0000-0002-7204-5000 Kurosh Rad-Moghadam Chemistry Department, University of Guilan, P.O. Box 41335-19141, Rasht, Iran. Tahereh Naghdi Department of Chemistry, College of Science, University of Guilan, Rasht, zip code 41335, I.R. Iran Journal Article 2024 02 03 This paper describes the applicability of 1,3-dichloro-5,5-dimethylhydantoin, as a cheap, stable and commercially available catalyst, in the promotion of the synthesis of 1,8-dioxo-octahydro-xanthenes (DOXOs) via the one-pot condensation of aldehydes and cyclic 1,3-dicarbonyl compounds. This novel synthetic method has the advantages of high yields, short reaction times, low cost and availability of the catalyst, solvent-free reaction conditions, simplicity and easy work-up compared to the conventional methods reported in the literature.