Synthesis of 1,3,5-tri-substituted pyrazoles promoted by P2O5.SiO2

  1. Department of Organic Chemistry, Faculty of Chemistry, University of Kashan, Kashan, Iran
  2. Department of Chemistry, College of Science, Yazd University, P. O. Box 89195-741, Yazd. Iran.
  3. Department of Chemistry, College of Science, Yazd University, P.O.Box 89195-741, Yazd, I.R.Iran.

Published in Issue 2024-02-03

How to Cite

Bamoniri, A., Mirjalili, B. F., Jafari, A. A., & Abasaltian, F. (2024). Synthesis of 1,3,5-tri-substituted pyrazoles promoted by P2O5.SiO2. Iranian Journal of Catalysis, 2(2). https://oiccpress.com/ijc/article/view/3722

PDF views: 225

HTML views: 16

Abstract

Silica supported phosphorus pentoxide (P2O5·SiO2) is an efficient catalyst for synthesis of 1,3,5-substituted pyrazoles via the condensation of 1,3-diketones and hydrazines. Simplicity of procedure, mild condition, being solvent-free, high yields, and easy workup are some advantages of this protocol.

Keywords

  • 3-diketones. Hydrazines,
  • 5-tri-substituted pyrazoles,
  • P2O5.SiO2,
  • Solvent-free