OICC Press Iranian Journal of Catalysis 2345-4865 2 2 2024 02 03 Synthesis of 1,3,5-tri-substituted pyrazoles promoted by P2O5.SiO2 EN Abdolhamid Bamoniri Department of Organic Chemistry, Faculty of Chemistry, University of Kashan, Kashan, Iran 0000-0002-8911-2433 BiBi Fatemeh Mirjalili Department of Chemistry, College of Science, Yazd University, P. O. Box 89195-741, Yazd. Iran. Abbas Ali Jafari Department of Chemistry, College of Science, Yazd University, P.O.Box 89195-741, Yazd, I.R.Iran. Fatemeh Abasaltian Department of Chemistry, College of Science, Yazd University, P.O.Box 89195-741, Yazd, I.R.Iran. Journal Article 2024 02 03 Silica supported phosphorus pentoxide (P2O5·SiO2) is an efficient catalyst for synthesis of 1,3,5-substituted pyrazoles via the condensation of 1,3-diketones and hydrazines. Simplicity of procedure, mild condition, being solvent-free, high yields, and easy workup are some advantages of this protocol.