Synthesis of novel tridentate ligand-based palladium catalyst and investigation of its reactivity towards Suzuki, Sonogashira and Heck coupling reactions

Abstract

We have demonstrated a simple and efficient route for the synthesis of a novel imine based tridentate ligand and its Pd-complex to investigate the C-C cross-coupling reactions, that involve column chromatography purification in only one step. The catalytic activity of the newly synthesized catalyst was studied for the Suzuki, Sonogashira and, Heck cross-coupling reactions under mild conditions. All synthesized molecules are thoroughly characterized by IR and NMR techniques. The pro-ligand was characterized by a single Crystal X-ray diffraction study. The catalyst has excellent activity and good yield was obtained with minimum catalyst loading. The obtained yields are good to excellent.