OICC Press Iranian Journal of Catalysis 2345-4865 10 4 2024 02 03 Synthesis of novel tridentate ligand-based palladium catalyst and investigation of its reactivity towards Suzuki, Sonogashira and Heck coupling reactions EN Rajendran Nagarajan Department of Chemistry, Kongju National University, Kongju, Chungnam, 32588, Republic of Korea Panneer Selvam Rajeswari Department of Applied Chemistry, Karunya Institute of Technology and Sciences, Karunyar Nagar, Coimbatore, 641114, India Lourdusamy Emmanuvel Department of Applied Chemistry, Karunya Institute of Technology and Sciences, Karunyar Nagar, Coimbatore, 641114, India Journal Article 2024 02 03 We have demonstrated a simple and efficient route for the synthesis of a novel imine based tridentate ligand and its Pd-complex to investigate the C-C cross-coupling reactions, that involve column chromatography purification in only one step. The catalytic activity of the newly synthesized catalyst was studied for the Suzuki, Sonogashira and, Heck cross-coupling reactions under mild conditions. All synthesized molecules are thoroughly characterized by IR and NMR techniques. The pro-ligand was characterized by a single Crystal X-ray diffraction study. The catalyst has excellent activity and good yield was obtained with minimum catalyst loading. The obtained yields are good to excellent.