Phytochemistry, traditional uses, and pharmacology of the genus Ekebergia (Meliaceae): A review

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  • Guy Paulin Mouthe Kemayou1,
  • Sorelle Fotsing Kache2,
  • Liliane Clotilde Dzouemo3,
  • Gervais M. Happi*4,
  • Simeon Fogue Kouam5,
  • Jean Claude Tchouankeu2,
  1. Department of Chemistry, Higher Teacher Training College, University of Yaounde I, P.O. Box 47, Yaounde, Cameroon|Department of Organic Chemistry, Faculty of Sciences, University of Yaounde I, P.O. Box 812, Yaounde, Cameroon
  2. Department of Organic Chemistry, Faculty of Sciences, University of Yaounde I, P.O. Box 812, Yaounde, Cameroon
  3. Department of Chemistry, University of Douala, Faculty of Sciences, 24157 Douala, Cameroon
  4. Department of Chemistry, Higher Teacher Training College, University of Bamenda, P.O Box 39, Bambili, Cameroon
  5. Department of Chemistry, Higher Teacher Training College, University of Yaounde I, P.O. Box 47, Yaounde, Cameroon

Revised: 2021-04-18

Accepted: 2021-08-05

Published in Issue 2021-09-01

How to Cite

Mouthe Kemayou, G. P., Fotsing Kache, S., Dzouemo, L. C., M. Happi, G., Fogue Kouam, S., & Tchouankeu, J. C. (2021). Phytochemistry, traditional uses, and pharmacology of the genus Ekebergia (Meliaceae): A review. Trends in Phytochemical Research, 5(3), 110-125. https://oiccpress.com/tpr/article/view/11803

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Abstract

Ekebergia (Meliaceae) is a genus of flowering shrubs and trees widely distributed in the African continent. It is represented by four species namely E. capensis Sparrm, E. benguelensis Welw. ex C.DC, E. pterophylla (C.DC.) Hofmeyr and E. pumila I.M.Johnst. The information for this review has been collected via a survey performed through several online libraries including the Plantlist, Jstor, Scifinder, PubMed, Google Scholar, Web of Science and Dictionary of Natural Products. So far, about 69 distinct compounds have been isolated during the previous phytochemical studies of Ekebergia genus plants. These compounds belong to diverse classes of metabolites such as limonoids, triterpenoids, coumarins, steroids, alkaloids, stilbenes and phenolic compounds. Some of these isolates displayed various bioactivities including antiplasmodial, antimicrobial, antiproliferative or uterotonic activities. This review covers the traditional uses, the phytochemical and pharmacological investigations of the genus Ekebergia over the last four decades (1980 to 2020).

Keywords

  • Pharmacology,
  • Traditional uses,
  • Ekebergia,
  • Meliaceae,
  • chemical constituents
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