Sonneratinone: A new antimicrobial benzofuranone derivative from the endophytic fungus Aspergillus niger isolated from the mangrove plant Sonneratia apetala Buch.-Ham

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  • Tauhidur Rahman Nurunnabi1,
  • Shaymaa Al-Majmaie2,
  • Lutfun Nahar3,
  • Ismini Nakouti2,
  • S. M. Mahbubur rahman4,
  • MD. Hossain Sohrab5,
  • MD. Morsaline Billah4,
  • Fyaz MD. Ismail2,
  • George P. Sharples2,
  • Satyajit D. Sarker*2,
  1. Centre for Natural Products Discovery, School of Pharmacy and Biomolecular Sciences, Liverpool John Moores University, James Parsons Building, Byrom Street, Liverpool L3 3AF, United Kingdom |Biotechnology and Genetic Engineering Discipline, Khulna University, Khulna, Bangladesh
  2. Centre for Natural Products Discovery, School of Pharmacy and Biomolecular Sciences, Liverpool John Moores University, James Parsons Building, Byrom Street, Liverpool L3 3AF, United Kingdom
  3. Laboratory of Growth Regulators, Institute of Experimental Botany ASCR & Palacký University, Šlechtitelů 27, 78371 Olomouc, Czech Republic
  4. Biotechnology and Genetic Engineering Discipline, Khulna University, Khulna, Bangladesh
  5. Pharmaceutical Sciences Research Division, BCSIR Laboratories, Dhaka, Bangladesh

Revised: 2019-06-02

Accepted: 2019-08-26

Published in Issue 2019-09-01

How to Cite

Nurunnabi, T. R., Al-Majmaie, S., Nahar, L., Nakouti, I., Mahbubur rahman, S. M., Hossain Sohrab, M., Morsaline Billah, M., Ismail, F. M., Sharples, G. P., & Sarker, S. D. (2019). Sonneratinone: A new antimicrobial benzofuranone derivative from the endophytic fungus Aspergillus niger isolated from the mangrove plant Sonneratia apetala Buch.-Ham. Trends in Phytochemical Research, 3(3), 225-230. https://oiccpress.com/tpr/article/view/11758

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Abstract

A new antimicrobial benzofuranone derivative, named, sonneratinone (1), was isolated from the endophytic fungus Aspergillus niger, obtained from the leaves of Sonneratia apetala, a mangrove plant from the Sundarbans. Whilst the fungal strain was identified by macroscopic, microscopic and molecular techniques, the structure of the new compound was elucidated by spectroscopic means, e.g., 1D and 2D NMR, and HRESIMS. Sonneratinone (1) showed considerable antimicrobial activity against Micrococcus luteus, Staphylococcus aureus and Candida albicans in the resazurin 96-well microtitre plate antimicrobial assay.
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