10.1007/s40204-020-00144-1

Surface modification of electrospun silk/AMOX/PVA nanofibers by dielectric barrier discharge plasma: physiochemical properties, drug delivery and in-vitro biocompatibility

  • Namita Ojah1,
  • Rajiv Borah2,
  • Gazi Ameen Ahmed1,
  • Manabendra Mandal3,
  • Arup Jyoti Choudhury*1,
  1. Laboratory for Plasma Processing of Materials, Department of Physics, Tezpur University, Tezpur, Assam, 784028, IN
  2. Life Sciences Division, Institute of Advanced Study in Science and Technology, Guwahati, Assam, 781035, IN
  3. Department of Molecular Biology and Biotechnology, Tezpur University, Tezpur, Assam, 784028, IN

Published in Issue 2020-11-18

How to Cite

Ojah, N., Borah, R., Ahmed, G. A., Mandal, M., & Choudhury, A. J. (2020). Surface modification of electrospun silk/AMOX/PVA nanofibers by dielectric barrier discharge plasma: physiochemical properties, drug delivery and in-vitro biocompatibility. Progress in Biomaterials, 9(4 (December 2020). https://doi.org/10.1007/s40204-020-00144-1
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Abstract

Article Highlights Effect of O 2 DBD plasma treatment time on the surface properties of silk/AMOX/PVA nanofibers. Plasma treatment time of 1 min shows the highest rate of surface modifications in terms of chemical, mechanical, wettability and surface energy improvement. Increase in plasma treatment time up to 5 min results in continuous increasing drug release rate. The plasma treatment time does not cause any hemolytic effect, also improved cell viability and cell attachment with cell spreading is observed after 1−3 min of plasma treatment time.

Keywords

  • Silk,
  • Dielectric barrier discharge,
  • Surface modification,
  • Hydrophilicity,
  • Drug delivery,
  • Biocompatibility

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