10.1007/s40204-020-00133-4

Preparation and characterization of polyethylene terephthalate–chamomile oil blends with enhanced hydrophilicity and anticoagulant properties

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  • Maie A. Fadel1,
  • Nagwa A. Kamel*1,
  • Mirhane M. Darwish2,
  • Salwa L. Abd El-Messieh1,
  • Kamal N. Abd-EL-Nour1,
  • Wafaa A. Khalil2,
  1. Microwave Physics and Dielectrics Department, National Research Centre, Cairo, EG
  2. Biophysics Department, Faculty of Science, Cairo University, Giza, EG

Published in Issue 2020-06-21

How to Cite

Fadel, M. A., Kamel, N. A., Darwish, M. M., El-Messieh, S. L. A., Abd-EL-Nour, K. N., & Khalil, W. A. (2020). Preparation and characterization of polyethylene terephthalate–chamomile oil blends with enhanced hydrophilicity and anticoagulant properties. Progress in Biomaterials, 9(3 (September 2020). https://doi.org/10.1007/s40204-020-00133-4
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Abstract

Abstract New blend films based on polyethylene terephthalate (PET) with different concentrations (50, 100 and 200 µL) of chamomile oil (CAO) were prepared. The effect of oil on the dielectric properties, structural and surface properties of PET was studied. The wettability of the blend films was evaluated by contact angle measurements. In vitro platelet adhesion on the surface and coagulation assessment were conducted to evaluate the behavior of the new blends for blood contact applications. Results of the study indicate that the wettability of PET–CAO blends up to 100 µL has been enhanced relative to the pure PET as indicated by the decrease in contact angle measurements. The attenuation total reflection–Fourier transform infrared spectra of the blends confirmed the presence of chamomile oil in the polymer matrix and suggested the presence of interaction between them. The permittivity ε ′ values decreased by increasing oil content upto 100 µL. On the other hand, the values of dielectric loss ε ″ were found to increase by increasing oil content to 100 µL after which it decreased. The delay in partial thromboplastin time (PTT) of the blood would validate the anti-coagulant property of PET–CAO blends. The results demonstrated that the PET–CAO blends with concentration of 100 µL could be considered as a promising candidate material in blood contact application.

References

  1. Abd-El-Messieh and Abd-El-Nour (2003) Effect of curing time and sulfur content on the dielectric relaxation of styrene butadiene rubber 88(7) (pp. 1613-1621) https://doi.org/10.1002/app.11686
  2. Ajili (2003) Study on thermoplastic polyurethane/polypropylene (TPU/PP) blend as a blood bag material 89(9) (pp. 2496-2501) https://doi.org/10.1002/app.12180
  3. Al-Baroudi (2014) Hepatoprotective effect of chamomile capitula extract against 2, 4-dichlorophenoxyacetic acid-induced hepatotoxicity in rats (pp. 34-40)
  4. Balaji (2015) Microwave-assisted fibrous decoration of mPE surface utilizing Aloe vera extract for tissue engineering applications
  5. Breuer (1995) Photolytic surface modification of polymers with UV-laser radiation 9(3) (pp. 351-363) https://doi.org/10.1163/156856195X00545
  6. Ciko (2016) A study on oil extraction from Albanian chamomile and characterization by IR spectroscopy 11(2) (pp. 154-158)
  7. Contini (2011) Development of active packaging containing natural antioxidants (pp. 224-228) https://doi.org/10.1016/j.profoo.2011.09.035
  8. Eftekhari S, Mirzadeh H (2012) Plasma graft polymerization of acrylic acid and immobilization of heparin to improve blood compatibility of polyethylene terephthalate (PET). In: MRS online proceedings library archive, vol 1469
  9. Fadel MA et al (2019) Ultraviolet surface modification of polyethylene terephthalate (PET) for reducing thrombogenicity. Dr. Alfred Huthig Verlag Gmbh, Heidelberg, pp 34–39.
  10. https://kgk-rubberpoint.de
  11. Fadel (2020) Effect of microwave treatment on biophysical and surface properties of polyethylene terephthalate (PET) for blood contact applications (pp. 343-351) https://doi.org/10.1007/s40011-019-01107-8
  12. Gardiner P (1999) Chamomile (
  13. Matricaria recutita
  14. ,
  15. Anthemis nobilis
  16. ). Longwood herbal task force
  17. Jaganathan (2017) Manufacturing and characterization of novel electrospun composite comprising polyurethane and mustard oil scaffold with enhanced blood compatibility 9(5) https://doi.org/10.3390/polym9050163
  18. Jaganathan (2018) Blood compatibility and physicochemical assessment of novel nanocomposite comprising polyurethane and dietary carotino oil for cardiac tissue engineering applications 135(3) https://doi.org/10.1002/app.45691
  19. Jain and Joshi (2012) Coumarin: chemical and pharmacological profile 2(6) (pp. 236-240)
  20. Kamal AH et al (2007) How to interpret and pursue an abnormal prothrombin time, activated partial thromboplastin time, and bleeding time in adults. In: Mayo Clinic proceedings, Elsevier
  21. Kuete (2013) Newnes
  22. Kun, W., et al. (2012). The surface modification of a polyethylene (PE) film using an air coplanar barrier discharge plasma at atmosphere pressure. In: 2nd international conference on electronic and mechanical engineering and information technology, Atlantis Press
  23. Manroe (1979) The neonatal blood count in health and disease. I. Reference values for neutrophilic cells 95(1) (pp. 89-98) https://doi.org/10.1016/S0022-3476(79)80096-7
  24. Nair and Laurencin (2005) (pp. 47-90) Springer
  25. Pierre (2005) Inhibitory effect of aqueous extracts of some herbs on human platelet aggregation in vitro 16(8) (pp. 469-473) https://doi.org/10.1080/09537100500129540
  26. Shi (2010) Solvent effects in the polyethylene terephthalate surface modification by cold argon plasma-induced grafting polymerization of methacrylic acid 117(3) (pp. 1460-1468)
  27. Singh (2011) Chamomile (Matricaria chamomilla L.): an overview 5(9) https://doi.org/10.4103/0973-7847.79103
  28. Stanger (2012) Anticoagulant activity of select dietary supplements 70(2) (pp. 107-117) https://doi.org/10.1111/j.1753-4887.2011.00444.x
  29. Taraj (2017) Eco-extraction of Albanian chamomile essential oils by liquid CO2 at different temperatures and characterisation by FTIR spectroscopy (pp. 117-124)
  30. Ul Ahad (2014) Surface modification of polymers for biocompatibility via exposure to extreme ultraviolet radiation 102(9) (pp. 3298-3310) https://doi.org/10.1002/jbm.a.34958