10.1007/s40204-019-0117-6

The effect of sodium and magnesium ions on the properties of calcium–phosphate biomaterials

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  • Ekaterina Lyutova*1,
  • Lyudmila Borilo1,
  • Elena Izosimova1,
  1. National Research Tomsk State University, Tomsk, RU
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Published in Issue 2019-05-24

How to Cite

Lyutova, E., Borilo, L., & Izosimova, E. (2019). The effect of sodium and magnesium ions on the properties of calcium–phosphate biomaterials. Progress in Biomaterials, 8(2 (June 2019). https://doi.org/10.1007/s40204-019-0117-6
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Abstract

Abstract A calcium–phosphate system was obtained by sol–gel method from 0.4 M solutions based on ethyl alcohol, tetraethoxysilane, phosphoric acid, calcium nitrate, and magnesium nitrate, sodium chloride. Compositions with different contents of CaO, Na 2 O, and MgO were prepared. After maturation of the solutions, heat treatments were applied at 60 °C for 30 min; and followed by 600 °C and 800 °C for 1 h. Solution with 20 wt% MgO was found suitable for film production. The physicochemical processes of the formation of materials were studied, including the main stages: removal of physically bound and chemically bound water, combustion of alcohol and the products of thermo-oxidative destruction of ethoxy groups, and crystallization processes. The phase composition and structure of the films obtained were established at 600 °C and above when crystalline forms of SiO 2 , CaSiO 3 , Ca 2 P 2 O 7 , and complex phosphates were fixed. In the system with the addition of magnesium ions, β-cristobalite SiO 2 and stenfieldt Mg 3 Ca 3 (PO 4 ) 4 were detected; however, a crystalline sample could only be obtained at 800 °C. In the system with sodium ions, chemical compounds Ca 5 (PO 4 ) 3 Cl, NaCl, and SiO 2 were determined. A uniform film coating was formed on the surface of the substrate. The introduction of sodium oxide into the SiO 2 –P 2 O 5 –CaO system increased the bioactivity of the materials obtained.

Keywords

  • Calcium–phosphate materials,
  • Biomaterial,
  • Sol–gel synthesis
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