10.1007/s40204-014-0030-y

Advancement of wound care from grafts to bioengineered smart skin substitutes

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  • Robin Augustine1,
  • Nandakumar Kalarikkal2,
  • Sabu Thomas*3,
  1. International and Interuniversity Centre for Nanoscience and Nanotechnology, Mahatma Gandhi University, Kottayam, Kerala, 686 560, IN
  2. International and Interuniversity Centre for Nanoscience and Nanotechnology, Mahatma Gandhi University, Kottayam, Kerala, 686 560, IN School of Pure and Applied Physics, Mahatma Gandhi University, Kottayam, Kerala, 686 560, IN
  3. International and Interuniversity Centre for Nanoscience and Nanotechnology, Mahatma Gandhi University, Kottayam, Kerala, 686 560, IN School of Chemical Sciences, Mahatma Gandhi University, Kottayam, Kerala, 686 560, IN
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Published in Issue 2014-11-14

How to Cite

Augustine, R., Kalarikkal, N., & Thomas, S. (2014). Advancement of wound care from grafts to bioengineered smart skin substitutes. Progress in Biomaterials, 3(2-4 (December 2014). https://doi.org/10.1007/s40204-014-0030-y
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Abstract

Abstract This review gives a brief description on the skin and its essential functions, damages or injury which are common to the skin and the role of skin substitute to replace the functions of the skin soon after an injury. Skin substitutes have crucial role in the management of deep dermal and full thickness wounds. At present, there is no skin substitute in the market that can replace all the functions of skin ‘and the research is still continuing for a better alternative. This review is an attempt to recollect and report the past efforts including skin grafting and recent trends like use of bioengineered smart skin substitutes in wound care. Incorporation functional moieties like antimicrobials and wound healing agents are also described.

Keywords

  • Skin substitutes,
  • Skin grafts,
  • Wound healing,
  • Angiogenesis,
  • Smart biomaterials
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References

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