10.1007/s40204-022-00193-8

Influence of alumina substrates open porosity on calcium phosphates formation produced by the biomimetic method

  • Isabela R. Lavagnini*1,
  • João V. Campos1,
  • Denise Osiro1,
  • Julieta A. Ferreira1,
  • Luiz A. Colnago2,
  • Eliria M. J. A. Pallone3,
  1. Postgraduate Programme in Materials Science and Engineering, University of São Paulo, USP/FZEA, Pirassununga, SP, 13635-900, BR
  2. Brazilian Agricultural Research Corporation, EMBRAPA Instrumentation, São Carlos, SP, 13561-206, BR
  3. Postgraduate Programme in Materials Science and Engineering, University of São Paulo, USP/FZEA, Pirassununga, SP, 13635-900, BR Department of Biosystem Engineering, Faculty of Animal Science and Food Engineering (FZEA), University of São Paulo (USP), Pirassununga, SP, 13635-900, BR

Published in Issue 2022-06-23

How to Cite

Lavagnini, I. R., Campos, J. V., Osiro, D., Ferreira, J. A., Colnago, L. A., & Pallone, E. M. J. A. (2022). Influence of alumina substrates open porosity on calcium phosphates formation produced by the biomimetic method. Progress in Biomaterials, 11(3 (September 2022). https://doi.org/10.1007/s40204-022-00193-8
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Abstract

Abstract We evaluated the influence of the open porosity of alumina (Al 2 O 3 ) substrates on the phase formation of calcium phosphates deposited onto it surface. The Al 2 O 3 substrates were prepared with different porosities by the foam-gelcasting method associated with different amounts of polyethylene beads. The substrates were coated biomimetically for 14 and 21 days of incubation in a simulated body fluid (SBF). Scanning electron microscopy characterisation and X-ray computed microtomography showed that the increase in the number of beads provided an increase in the open porosity. The X-ray diffraction and infrared spectroscopy showed that the biomimetic method was able to form different phases of calcium phosphates. It was observed that the increase in the porosity favoured the formation of β-tricalcium phosphate for both incubation periods. The incubation period and the porosity of the substrates can influence the phases and the amount of calcium phosphates formed. Thus, it is possible to target the best application for the biomaterial produced.

Keywords

  • Al2O3,
  • Porous ceramic,
  • Biomimetic coating,
  • Calcium phosphates

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