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Keyword: Nanocrystalline magnesium aluminate

Original Article
Improving methodology for the preparation of highly substituted imidazoles using nano-MgAl2O4 as catalyst under microwave irradiation

An efficient synthesis of 2,4,5-trisubstituted and 1,2,4,5-tetrasubstituted imidazoles by one-step condensation of  an aldehyde, benzil, ammonium acetate and primary amine in the presence of nanocrystalline magnesium aluminate under microwave irradiation is described. The advantages of this catalyst are including simple work-up, low cost and reusability. Compared with conventional methods, the main advantages of the present […]