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Keyword: indole

Original Article
Synthesis and in-vitro antimicrobial screening of 3-cinnamoyl coumarin and 3-[3-(1H-indol-2-yl)-3-aryl-propanoyl]-2H-chromen-2-ones

An efficient synthesis of some novel coumarin derivatives via 1, 4- Michael addition of indole to coumarin chalcones catalyzed by cellulose sulphonic acid (CSA) under solvent free conditions is described. The corresponding Michael addition products were obtained in good to excellent yield. The synthesized compounds were screened for their antibacterial activity against E. coli, S. […]

Original Article
Ammonium monovanadate: a versatile and reusable catalyst for Friedel-Crafts alkylation and Michael addition of indoles

Ammonium monovanadate (NH4VO3) has been devoted as an efficient, commercially available, eco-friendly and reusable catalyst for the synthesis of bis(indolyl)methanes (BIMs), oxindole derivatives and also Michael adducts of indoles at 50 °C under solvent-free conditions. The reusability of this solid acid catalyst in addition with its selectivity has also been examined.

Original Article
Nano silica sulfuric acid catalyzed synthesis of 2-substituted aryl (indolyl) kojic acid derivatives

Nano silica sulfuric acid as a solid acid, was described to be an effective catalyst for one-pot three-component reaction of kojic acid, aryl aldehydes and indoles for the preparation of 2-substituted aryl (indolyl) kojic acid derivatives. The catalyst was prepared by combination of chlorosulfonic acid to nano silica gel. The size of nanoparticles were observed […]

Original Article
A green synthesis of di-indolyloxindols catalyzed by CuO/g-C3N4 nanocomposite under mild conditions

In this study, novel CuO/g-C3N4 nanocomposite was simply synthesized by impregnation of g-C3N4 with CuO nanoparticles. Then, the heterogeneous catalyst was characterized by various techniques including Fourier transform infrared spectroscopy (FT-IR), X-ray diffraction (XRD), thermogravimetric analysis (TGA) and transmission electron microscopy (TEM). Moreover, the Friedel–Crafts 3-indolylation reaction of isatin with indole derivatives in water as […]

Original Article
Synthesis, characterization and immobilization of cobalt (III) salen complex on CoFe2O4@SiO2 nanoparticle and their application in the synthesis of di-indolyloxindole

The preparation, characterization, and immobilization of cobalt (III) salen complex on CoFe2O4@SiO2 nanoparticle (CoFe2O4@SiO2@ Co(III) salen complex) are described. Co(III) salen complex loaded on ferrite cobalt-silica nanoparticle is characterized by TEM, SEM-EDX, VSM and FT-IR analyses. The efficiency of CoFe2O4@SiO2@Co(III) salen complex as a catalyst was carried out in the 3-indolylation reaction of indole with […]