In this work, an efficient and green procedure for the synthesis of dihydro-2-oxypyrroles has been developed. One-pot four-component condensation reaction of aniline derivatives (2 mmol), dialkyl acetylene dicarboxylate (1 mmol), and aldehydes ( 1 mmol) was done in ethanol at 65 °C in the presence of nano-Fe3O4@SiO2/SnCl4 as a magnetically reusable heterogeneous acid catalyst. The […]
Tetrazoles have many interesting futures and applications in drug and energy industries. 5-Substituted 1H-tetrazoles were synthesized via [2+3] cycloaddition reaction of aryl or alkyl nitriles with sodium azide in the presence of [email protected] as catalyst in DMF under reflux conditions. The catalyst was removed from reaction mixture by an external magnet and was reusable for […]