Trans-3,5-dihydroperoxy-3,5-dimethyl-1,2-dioxolane/HOAc/KI system as a new and mild catalyst for efficient synthesis of 1H-benzimidazoles and 1H-benzothiazoles in water

Authors

• Kaveh Khosravi ¹
• Akbar Mobinikhaledi ²
• Samira Kazemi ²
• Davood Azarifar ³
• Payam Rahmani ⁴

1. Faculty of Science, Department of Chemistry, Arak University, Arak 38156-8-8349, Iran.
2. Department of Chemistry, Faculty of Science, Arak University, Arak 38156-8-8349, Iran
3. Faculty of Chemistry, Bu-Ali Sina University, 65178, Hamedan, Iran
4. Department of Organic Chemistry, Faculty of Chemistry, Bu-Ali Sina University, Hamedan, 6517838683 Iran.

Abstract

An efficient method has been developed for the catalysis of condensation of 1,2-phenylenediamines and 2-aminothiophenoles with different aldehydes into their corresponding 2-aryl-1H-benzimidazoles and 2-aryl-1H-benzothiazoles under mild condition. In this method, trans-3,5-dihydroperoxy-3,5-dimethyl-1,2-dioxolane (DHPDMDO)/HOAc/KI system was used as a novel and effective oxidant in water at room temperature with excellent results.

Keywords

• 5-dihydroperoxy-3
• 5-dimethyl-1
• 2-Aryl-1H-benzothiazoles
• 2-Aryl-1-arylmethyl-1H-benzimidazoles
• Condensation
• 2-dioxolane (DHPDMDO)
• Trans-3