L-proline: An efficient catalyst for the synthesis of quinoline derivatives in aqueous media

Authors

• Elham Davoodi ¹
• Leila Youseftabar-Miri ²
• Hamideh Hosseinjani-Pirdehi ³

1. Chemistry Department, Izeh Branch, Islamic Azad University, Izeh, Iran.
2. Department of Chemistry, Izeh Branch, Islamic Azad University, Izeh, Iran
3. Chemistry Department, University of Guilan, 41335-1914, Rasht, Iran.

Abstract

An efficient and direct procedure for the synthesis of benzo[h]-indeno[1,2-b]-quinoline derivatives has been described. The procedure employs a three-component condensation reaction in one-pot using 2H-indene-1, 3-dione, naphthalen-1-amine,and aldehydes in the presence of catalytic amount of L-prolinein aqueous media.

Keywords

• Multicomponent reactions
• Aqueous media
• L-proline
• Quinoline derivatives