Fe3O4@nano-dextrin/Ti(IV) as a bio-based magnetic nano-catalyst for facile synthesis of 2,3-dihydroquinazolin-4(1H)-ones

Authors

• Elaheh Babaei ¹
• Bi Bi Fatemeh Mirjalili * ²

1. Department of Chemistry, College of Science, Yazd University, Yazd, 89195-741, I. R. Iran.
2. Department of Chemistry, College of Science, Yazd University, Yazd, P.O. Box 89195-741, Iran

Abstract

A bio-based magnetic nano-catalyst (Fe₃O₄@nano-dextrin/Ti(IV)) was synthesized via the preparation of Fe₃O₄@nano-dextrinas magnetic support and then its treatment with titanium tetrachloride (TiCl₄). The properties of this catalyst were characterized by different kinds of techniques such as FT-IR, FESEM, TEM, ICP, XRF, VSM and TGA. As a first report, the catalytic activity of Fe₃O₄@nano-dextrin/Ti(IV) was investigated in the synthesisof 2,3-dihydroquinazolin-4(1H)-ones via condensation between 2-aminobenzamide and aldehyde under mild conditions. Good efficiency, a high percentage of product yields, simplicity of operation and easy recovery and reuse of catalyst are some benefits of this protocol.

Keywords

• 2. 3-Dihydroquinazolin-4(1H)-ones
• Multi-component reactions
• Fe3O4@nano-dextrin/Ti(IV)
• Magnetic nano-catalyst
• Lewis acid catalyst