Efficient synthesis of bis(indolyl)methanes catalyzed by (PhCH2PPh3)+Br- under solvent-free conditions

Authors

• Farhad Shirini ¹
• Masoumeh Abedini ²
• Manouchehr Mamaghani ³
• Arman Rahmaninia ²

1. Department of Chemistry, College of Science, University of Guilan, Rasht, 41335, Iran.
2. Department of Chemistry, College of Science, University of Guilan, Rasht, zip code 41335, I.R. Iran.
3. Department of Chemistry, Faculty of Sciences, University of Guilan, P.O. Box 41335-1914, Rasht, Iran.

Abstract

Benzyltriphenylphosphonium bromide (BTPB) has been applied as an efficient catalyst for the preparation of bis(indolyl)methanes (BIMs) via electrophilic substitution of indoles with aldehydes in the absence of solvent.

Keywords

• Solvent-free conditions
• Aldehydes
• Benzyltriphenylphosphonium bromide
• Indoles
• Bis(indolyl)methanes