Boric acid as a highly efficient and reusable catalyst for the one-pot synthesis of 1,8-dioxo-octahydroxanthenes under solvent-free conditions

Authors

• Sobhan Rezayati ^{1, 2}
• Rahimeh Hajinasiri ²
• Zahra Erfani ¹
• Saman Rezayati ¹
• Saeid Afshari-sharifabad ²

1. Department of Chemistry, Payame Noor University, PO BOX 19395-4697, Tehran, Iran.
2. Chemistry Department, Qaemshahr Branch, Islamic Azad University, Qaemshahr, Iran.

Abstract

An efficient and simple procedure for the synthesis of 1,8-dioxo-octahydroxanthenes from the aromatic aldehydes and 5,5-dimethylcyclohexane-1,3-dione (dimedone) in the presence of boric acid [BO3H3 or B(OH)3] as an inexpensive and reusable catalyst is described. The salient features of this methodology are: the elimination of corrosive liquid acids, high yields, simple methodology, short reaction times, easy work-up and green heterogeneous catalyst.

Keywords

• Boric acid
• Dimedone
• Solid acid
• One-pot reaction.
• Xanthenes
• Aromatic aldehyde