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Keyword: Synergistic effect

Original Article
Fabrication of PCL-PEG-PCL nanocarrier for Co-loading of Docetaxel/Quercetin and assessment of its effect on growth inhibition of human liver cancer (Hep-G2) cell line

Nanoscale co-delivery systems are advanced examples of combination therapies that can provide better therapeutic performance. Here, we tried to improve the solubility, bioavailability, synergistic, and potentiation properties of docetaxel (DTX) using co-loading of DTX and quercetin (Qu) into PCL-PEG-PCL-based nanocarrier. To this end, PCL-PEG-PCL copolymer synthesized, then, DTX and DTX/Qu loaded into this nanocarrier, separately, […]