Two component reaction for the synthesis of Quinolines in the presence of γ-Al2O3 and Cu/ZnO nanoparticles

Authors

• M. Qandalee ¹
• M. Hatami ²
• A. Esmaeilzadeh ³
• A. Shojaeian ³
• P. Biparva ⁴

1. Department of biology, Garmsar branch, Islamic Azad University, Garmsar, Iran.
2. Polymer Research Laboratory, University of Bonab, Bonab, I. R. Iran.
3. Department of Chemistry, Ayatollah Amoli Branch, Islamic Azad University, Amol, Iran.
4. Department of Basic Sciences, Sari Agricultural Sciences and Natural Resources University, P.O. Box 578, Sari 4818168984, Iran.

Abstract

Two-component reaction of 2-aminobenzophenones with acetylenic esters in the presence of γ-Al₂O₃ and Cu/ZnO as suitable heterogeneous catalysts has been studied. Nano γ-Al₂O₃ and Cu/ZnO showed high activities when used as surface catalysts for the synthesis of quinoline derivatives. After completion of the reaction, the catalyst was recovered and reused several times under the same reaction conditions.

Keywords

• Nano γ-Al2O3
• Acetylenic Esters
• Nano Cu/ZnO
• Quinoline
• 2-Aminobenzophenones