Simulation study of the performance of a biologically sensitive field effect transistor

Authors

• K. Talukdar ¹
• M. Bhushan ²
• A. Kasi Viswanathc ²
• A. K. Mitrad ¹

1. Department of Physics, NIT-Durgapur-713209, West Bengal, India.
2. Centre for Nanoscience and Technology, Pondicherry University, Kalapet, Puducherry-605014, India.

Abstract

The transformation of biochemical information into a physical or chemical signal is the basic idea behind a biosensor. The efficient detection of charged biomolecules by biosensor with appropriate device has caught tremendous research interest in the present decade. The present work is related to the simulation study of the performance of a functionalized surface of a biologically sensitive field-effect transistor. The detection process is less time consuming and less expensive as it combines a biological sensor and a measurement circuit in a small chip. In this model, a constant potential difference is maintained in between the two electrodes, one of which is functionalized with different types of biomolecules. With the number of double strand DNA oligomers, the concentration of Na⁺ and Cl^– ions in the electrolyte in between the electrodes is changed, resulting in changes in surface charge density and dipole moment. Monte-Carlo simulation is performed in a neutral environment after functionalizing one electrode by double strand DNA.

Keywords

• Chemical potential
• BioFET
• Monte-Carlo simulation
• Dipole moment
• Ionic concentration
• Biosensor