Antifungal activity of silver nanoparticles on some of fungi

Authors

• A. Nasrollahi ¹
• Kh. Pourshamsian ²
• P. Mansourkiaee ³

1. Department of biology, Faculty of science, Islamic azad university, Tonekabon branch, Tonekabon, Iran.
2. Department of chemistry, Faculty of science, Islamic azad university, Tonekabon branch, Tonekabon, Iran.
3. Basic science student, Member of young researchers club, Islamic azad university of Tonekabon, Iran.

Abstract

In this study, we investigated the antifungal effects of silver nanoparticles (Ag-Nps) on Candida albicans (ATCC 5027), Saccharomyces cerevisiae (ATCC 5027). Investigating method by using Minimum Inhibitory Concentration (MIC) technique, some of drugs including Amphotericin B, Fluconazole and synthesized Ag-Nps have been obtained on the fungi and the changes on membrane reactions of yeasts have been elucidated by Scanning Electron Microscopy (SEM). The present study indicates Ag-Nps has considerable antifungal activity comparison with other antifungal drugs, so deserving further investigation for clinical applications.

Keywords

• Antifungal activity
• Minimum inhibitory concentration (MIC)
• Silvernanoparticles (Ag-Nps)