10.57647/j.ijnd.2025.1604.30

Evaluation of the catalytic and in-vitro anticancer potential of Gold nanoparticles synthesized using clammy cherry (Cordia Obliqua Willd)

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  • Anjaly Mathew1,
  • Aswathy Jayaprakash2,
  • Aneetha Mundakassery Ratnamma2,
  • Sandhya Paleri Veetil2,
  • Zeena Pallimittath Hamza2,
  • Amrutha Sivarajan2,
  • Rejimon Pooppanathara Kochappan2,
  • Ramla Kudukkil Thahathuveettil3,
  • Jasmin Jose4,
  • Kavitha Jacob5,
  • Femina Kanjirathamthadathil Saidu*2,
  1. Department of Chemistry, Sree Neelakanta Government Sanskrit College, Pattambi, Kerala, India
  2. Department of Chemistry, Maharaja’s College Ernakulum, Kerala, India
  3. Department of Physics, PTM Government College Perinthalmanna, Malappuram, Kerala, India
  4. Department of Basic Science and Humanities, Jyothi Engineering College Cheruthuruthy, Thrissur, Kerala, India
  5. Department of Chemistry, Bishop Abraham Memorial College, Thuruthicadu, Pathanamthitta, Kerala, India
Evaluation of the catalytic and in-vitro anticancer potential of Gold nanoparticles synthesized using clammy cherry (Cordia Obliqua Willd)

Received: 2025-01-20

Revised: 2025-04-14

Accepted: 2025-05-05

Published in Issue 2025-05-17

Copyright (c) -1 Anjaly Mathew, Aswathy Jayaprakash, Aneetha Mundakassery Ratnamma, Sandhya Paleri Veetil, Zeena Pallimittath Hamza, Amrutha Sivarajan, Rejimon Pooppanathara Kochappan, Ramla Kudukkil Thahathuveettil, Jasmin Jose, Kavitha Jacob, Femina Kanjirathamthadathil Saidu (Author)

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This work is licensed under a Creative Commons Attribution 4.0 International License.

How to Cite

Mathew, A. ., Jayaprakash, A. ., Mundakassery Ratnamma, A. ., Paleri Veetil, S. ., Pallimittath Hamza, Z. ., Sivarajan, A. ., Pooppanathara Kochappan, R. ., Kudukkil Thahathuveettil, R. ., Jose, J. ., Jacob, K. ., & Kanjirathamthadathil Saidu, F. . (2025). Evaluation of the catalytic and in-vitro anticancer potential of Gold nanoparticles synthesized using clammy cherry (Cordia Obliqua Willd). International Journal of Nano Dimension, 16(4 (October 2025). https://doi.org/10.57647/j.ijnd.2025.1604.30
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Abstract

The synthesis of metal nanoparticles using environmentally friendly materials like fruit extracts offers the benefits of eco-friendliness and compatibility for pharmaceutical and other biomedical applications. The phytogenic synthesis can be conducted at convenient ease under microwave exposure. Here, through a microwave-assisted, fast, and cost-effective approach, monodispersed, spherical gold nanoparticles (AuNPs) with outstanding catalytic efficiency and anticancer activity were successfully synthesized using the extract of clammy cherry (Cordia Obliqua Willd) fruit. UV-Visible spectroscopic analysis, SEM, and HRTEM analysis have been used to characterize the prepared AuNPs. The electronic spectrum investigations have revealed that the MW power, length of exposure, gold ion concentration, and content of the cherry extract had a substantial impact on the rate of production, size, and surface plasmon absorption of AuNPs. According to TEM examinations, AuNPs are crystalline and spherical in shape, with a mean size of 11.7 nm. Anticancer activity of the stabilized AuNPs studied against Dalton's lymphoma Ascites cells confirmed that the stabilized AuNPs were highly effective for the apoptosis of cancer cells selectively. Furthermore, the AuNPs' catalytic efficiency in reducing hazardous organic pollutants viz. methyl orange (MO), methylene blue (MB), and methyl red (MR), 2-nitrophenol (2-NP) and 4-nitrophenol (4-NP), with borohydride-aided reduction proved appealing for environmental pollution remediation applications.

Keywords

  • Anticancer activity,
  • Catalysis,
  • Green synthesis,
  • Gold nanoparticles,
  • Methyl orange,
  • Microwave,
  • Nitrophenol,
  • Reduction
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