OICC Press International Journal of Nano Dimension 2228-5059 16 4 2025 05 17 Evaluation of the catalytic and in-vitro anticancer potential of Gold nanoparticles synthesized using clammy cherry (Cordia Obliqua Willd) 10.57647/j.ijnd.2025.1604.30 EN Anjaly Mathew Department of Chemistry, Sree Neelakanta Government Sanskrit College, Pattambi, Kerala, India https://orcid.org/0000-0002-5428-5545 Aswathy Jayaprakash Department of Chemistry, Maharaja’s College Ernakulum, Kerala, India Aneetha Mundakassery Ratnamma Department of Chemistry, Maharaja’s College Ernakulum, Kerala, India Sandhya Paleri Veetil Department of Chemistry, Maharaja’s College Ernakulum, Kerala, India Zeena Pallimittath Hamza Department of Chemistry, Maharaja’s College Ernakulum, Kerala, India Amrutha Sivarajan Department of Chemistry, Maharaja’s College Ernakulum, Kerala, India Rejimon Pooppanathara Kochappan Department of Chemistry, Maharaja’s College Ernakulum, Kerala, India Ramla Kudukkil Thahathuveettil Department of Physics, PTM Government College Perinthalmanna, Malappuram, Kerala, India Jasmin Jose Department of Basic Science and Humanities, Jyothi Engineering College Cheruthuruthy, Thrissur, Kerala, India Kavitha Jacob Department of Chemistry, Bishop Abraham Memorial College, Thuruthicadu, Pathanamthitta, Kerala, India Femina Kanjirathamthadathil Saidu Department of Chemistry, Maharaja’s College Ernakulum, Kerala, India Journal Article 2025 05 17 The synthesis of metal nanoparticles using environmentally friendly materials like fruit extracts offers the benefits of eco-friendliness and compatibility for pharmaceutical and other biomedical applications. The phytogenic synthesis can be conducted at convenient ease under microwave exposure. Here, through a microwave-assisted, fast, and cost-effective approach, monodispersed, spherical gold nanoparticles (AuNPs) with outstanding catalytic efficiency and anticancer activity were successfully synthesized using the extract of clammy cherry (Cordia Obliqua Willd) fruit. UV-Visible spectroscopic analysis, SEM, and HRTEM analysis have been used to characterize the prepared AuNPs. The electronic spectrum investigations have revealed that the MW power, length of exposure, gold ion concentration, and content of the cherry extract had a substantial impact on the rate of production, size, and surface plasmon absorption of AuNPs. According to TEM examinations, AuNPs are crystalline and spherical in shape, with a mean size of 11.7 nm. Anticancer activity of the stabilized AuNPs studied against Dalton's lymphoma Ascites cells confirmed that the stabilized AuNPs were highly effective for the apoptosis of cancer cells selectively. Furthermore, the AuNPs' catalytic efficiency in reducing hazardous organic pollutants viz. methyl orange (MO), methylene blue (MB), and methyl red (MR), 2-nitrophenol (2-NP) and 4-nitrophenol (4-NP), with borohydride-aided reduction proved appealing for environmental pollution remediation applications.