Facile synthesis of 5-substituted-1H-tetrazoles catalyzed by reusable nickel zirconium phosphate nanocatalyst

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  • Fatemeh Abrishami1,
  • Maryam Ebrahimikia2,
  • Fatemeh Rafiee3,
  1. Department of Chemistry and Chemical Engineering, Malek-Ashtar University of Technology, Tehran, Iran.
  2. Faculty of Chemistry and Chemical Engineering, Malek-Ashtar University of Technology, Tehran, Iran.
  3. Department of Organic Chemistry, Faculty of Chemistry, Alzahra University, Tehran, Iran

Published in Issue 2024-02-03

How to Cite

Abrishami, F., Ebrahimikia, M., & Rafiee, F. (2024). Facile synthesis of 5-substituted-1H-tetrazoles catalyzed by reusable nickel zirconium phosphate nanocatalyst. Iranian Journal of Catalysis, 6(3). https://oiccpress.com/ijc/article/view/3912

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Abstract

5-Substituted-1H-tetrazoles were synthesized by the [3 + 2] cycloaddition of sodium azide with various nitriles in the presence of nickel zirconium phosphate (NiZrP) as an effective heterogeneous catalyst in dimethylsulfoxide at 120 °C. This method has the advantages of good to high yields, simple methodology and easy work-up. The catalyst can be recovered by centrifuging and reused with good yields. There is no appreciable loss of catalytic activity up to five cycles. All aromatic nitriles with electron-donating group could be accomplished as well as that with electron-withdrawing groups. The structural characteristics of the catalyst are identified by scanning electron microscopy (SEM) and XRD instruments.

Keywords

  • 5-Substituted-1H-tetrazoles,
  • Cycloaddition,
  • Heterogeneous catalyst,
  • Nickel zirconium phosphate,
  • Reusable
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