Et3N/H2O: A green and inexpensive organocatalytic medium for efficient Baylis-Hillman reaction

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  • Mohammad Saeed Abaee1,
  • Ali Akbari1,
  • Mohammad Majid Mojtahedi1,
  1. Department of Organic Chemistry and Natural Products, Chemistry and Chemical Engineering Research Center of Iran, 17th Km, Pajoohesh Blvrd., Tehran-Karaj Highway, Tehran, Iran.

Published in Issue 2024-02-03

How to Cite

Abaee, M. S., Akbari, A., & Mojtahedi, M. M. (2024). Et3N/H2O: A green and inexpensive organocatalytic medium for efficient Baylis-Hillman reaction. Iranian Journal of Catalysis, 6(2). https://oiccpress.com/ijc/article/view/3897

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Abstract

A new organocatalyzed method is developed for BaylisâHillman reactions of cyclohex-2-enone with various aromatic aldehydes in the presence of water and catalytic quantities of triethylamine. All reactions take place at room temperature and relatively good yields of various products are obtained within a time frame which does not exceed 24 hours. The mild reaction conditions used in the present method and the versatility of the process are the main advantages of this procedure. As a result, products of the BaylisâHillman reaction of cyclohex-2-enone with various aromatic aldehydes bearing electron withdrawing and electron releasing groups are obtained under inexpensive organocatalytic conditions.

Keywords

  • Aqueous conditions,
  • Baylis-Hillman reaction,
  • Organocatalyst,
  • Room-tempearture
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