Nano silica sulfuric acid catalyzed synthesis of 2-substituted aryl (indolyl) kojic acid derivatives

PDF HTML
  • Zahra Lasemi1,
  • Bahareh Sadeghi2,
  • Fereshteh Amiri Tavasoli3,
  1. Department of Chemistry, Firoozkooh Branch, Islamic Azad University, Firoozkooh, Iran.
  2. Department of Chemistry, Central Tehran Branch, Islamic Azad University, Tehran, Iran
  3. Department of Chemistry, Islamic Azad University, Yazd Branch, P.O.Box 89195-155, Yazd, Iran

Published in Issue 2024-02-03

How to Cite

Lasemi, Z., Sadeghi, B., & Amiri Tavasoli, F. (2024). Nano silica sulfuric acid catalyzed synthesis of 2-substituted aryl (indolyl) kojic acid derivatives. Iranian Journal of Catalysis, 6(1). https://oiccpress.com/ijc/article/view/3883

PDF views: 117

HTML views: 17

Abstract

Nano silica sulfuric acid as a solid acid, was described to be an effective catalyst for one-pot three-component reaction of kojic acid, aryl aldehydes and indoles for the preparation of 2-substituted aryl (indolyl) kojic acid derivatives. The catalyst was prepared by combination of chlorosulfonic acid to nano silica gel. The size of nanoparticles were observed with SEM.All prepared compounds with melting points, 1H NMR and 13C NMR were characterized. High yields, simple operation, easy-work procedure, mild reaction conditions are some advantages of this protocol. The present method does not involve any hazardous organic solvent. Therefore, this procedure could be classified as green chemistry.

Keywords

  • Aldehyde,
  • indole,
  • Kojic acid,
  • Multi-component,
  • Nano silica sulfuric acid
PDF HTML