Synthesis of 2,4,5-triaryl-1H-imidazoles using a potent, green and reusable nano catalyst (FHS/SiO2)

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  • Mehdi Bakavoli1,
  • Hossein Eshghi1,
  • Ali Mohammadi1,
  • Hassanali Moradi1,
  • Javad Ebrahimi2,
  1. Department of Chemistry, Faculty of Sciences, Ferdowsi University of Mashhad, P.O. Box 91775-1436, Mashhad, Iran.
  2. Young Researchers Club, Islamic Azad University, Mashhad Branch

Published in Issue 2024-02-03

How to Cite

Bakavoli, M., Eshghi, H., Mohammadi, A., Moradi, H., & Ebrahimi, J. (2024). Synthesis of 2,4,5-triaryl-1H-imidazoles using a potent, green and reusable nano catalyst (FHS/SiO2). Iranian Journal of Catalysis, 5(3). https://oiccpress.com/ijc/article/view/3857

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Abstract

A simple, green and efficient method for synthesis of 2,4,5-trisubstituted imidazoles is described via three-component cyclocondensation of benzil or benzoin, aldehyde and ammonium acetate by using the nano SiO2-supported ferric hydrogen sulfate (FHS/SiO2), as a catalyst, under solvent-free conditions. The nano SiO2 support and catalyst were characterized by X-ray diffraction (XRD), transmission electron microscopy (TEM) and IR spectroscopy. In this project, the optimum conditions such as: reaction temperature, reaction time and amount of catalyst were investigated. The major advantages of the present method are high yields, shorter reaction times, easy work-up, purification of products by non-chromatographic method and the reusability of the catalyst.

Keywords

  • 5-Trisubstituted imidazoles,
  • Ferric hydrogen sulfate.,
  • Heterogeneous catalyst,
  • Nano-catalyst,
  • Solvent-free synthesis
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