A facile one-pot four-component synthesis of dihydropyrrol-2-ones using Cl3CCO2H

PDF HTML
  • Nourallah Hazeri1,
  • Malek Taher Maghsoodlou1,
  • Sajad Mohamadian-Souri2,
  • Mojtaba Lashkari3,
  • Majid Ghashang4,
  1. Chemistry Department, Faculty of Science, University of Sistan and Baluchestan, Zahedan, Iran
  2. Department of Chemistry, Faculty of Science, University of Sistan & Baluchestan, P. O. Box 98135-674 Zahedan, Iran
  3. Faculty of Science, Velayat University, Iranshahr, Iran.
  4. Department of Chemistry, Najafabad Branch, Islamic Azad University, P.O. Box: 517; Najafabad, Iran

Published in Issue 2024-02-03

How to Cite

Hazeri, N., Maghsoodlou, M. T., Mohamadian-Souri, S., Lashkari, M., & Ghashang, M. (2024). A facile one-pot four-component synthesis of dihydropyrrol-2-ones using Cl3CCO2H. Iranian Journal of Catalysis, 5(1). https://oiccpress.com/ijc/article/view/3826

PDF views: 151

HTML views: 7

Abstract

A convenient synthesis of different types of polyfunctional dihydropyrrol-2-ones via one-pot four component reactions of formaldehyde, dialkyl acetylenedicarboxylates and amines, catalyzed by trichloroacetic acid (Cl3CCO2H) at room temperature has been investigated. The significant advantages of this synthetic method are mild reaction conditions, available and inexpensive material, short reaction times, good yields, simple work-up.

Keywords

  • Aldehyde,
  • amine,
  • Dialkyl acetylenedicarboxylate,
  • Dihydro-2-oxypyrroles
PDF HTML