Highly efficient synthesis of carboacyclic nucleosides catalyzed by zinc oxide in 1-butyl-3-methylimidazolium bromide (ZnO/[bmim]Br)

PDF HTML
  • Tarlan Salehi-Hamzehkhani1,
  • Marzieh Hatami1,
  • Abdolkarim Zare2,
  • Ahmad Reza Moosavi-Zare3,
  • Abolfath Parhami1,
  • Zahra Khedri1,
  • Hamideh Kabgani1,
  • Mohammad Beikagha1,
  • Raheleh Salamipoor1,
  1. Department of Chemistry, Payame Noor University, P.O. Box 19395-3697, Tehran, Iran.
  2. Department of Chemistry, Payame Noor University, PO Box 19395-3697, Tehran, Iran
  3. Department of Chemistry, Sayyed Jamaleddin Asadabadi University, Asadabad, 6541861841, Iran.

Published in Issue 2024-02-03

How to Cite

Salehi-Hamzehkhani, T., Hatami, M., Zare, A., Moosavi-Zare, A. R., Parhami, A., Khedri, Z., Kabgani, H., Beikagha, M., & Salamipoor, R. (2024). Highly efficient synthesis of carboacyclic nucleosides catalyzed by zinc oxide in 1-butyl-3-methylimidazolium bromide (ZnO/[bmim]Br). Iranian Journal of Catalysis, 4(4). https://oiccpress.com/ijc/article/view/3824

PDF views: 136

HTML views: 10

Abstract

Michael addition of pyrimidine and purine nucleobases to substituted as well as unsubstituted α,β-unsaturated esters efficiently proceeds in the presence of catalytic amount of zinc oxide in ionic liquid 1-butyl-3-methylimidazolium bromide (ZnO/[bmim]Br) under microwave irradiation to afford carboacyclic nucleosides, as biologically important compounds, in good to excellent yields and in short reaction times.

Keywords

  • 1-Butyl-3-methylimidazolium bromide ([bmim]Br),
  • Carboacyclic nucleoside,
  • Ionic liquid,
  • Michael addition,
  • Microwave irradiation,
  • Zinc oxide
PDF HTML