Ultrasound based method for one-pot synthesis of substituted imidazoles using SiO2-OSbCl2 as highly effective and reusable catalyst

PDF HTML
  • Javad Safari1,
  • Zohre Zarnegar2,
  • Simin Naseh2,
  • Zahra Akbari2,
  1. Laboratory of Organic Compound Research, Department of Organic Chemistry, College of Chemistry, University of Kashan, P.O. Box: 87317-51167 Kashan, I.R. Iran.
  2. Laboratory of Organic Compound Research, Department of Organic Chemistry, College of Chemistry, University of Kashan, P.O. Box: 87317-51167, Kashan, I.R., Iran.

Published in Issue 2024-02-03

How to Cite

Safari, J., Zarnegar, Z., Naseh, S., & Akbari, Z. (2024). Ultrasound based method for one-pot synthesis of substituted imidazoles using SiO2-OSbCl2 as highly effective and reusable catalyst. Iranian Journal of Catalysis, 4(3). https://oiccpress.com/ijc/article/view/3801

PDF views: 172

HTML views: 14

Abstract

A simple highly versatile and efficient sonochemical synthesis of 1,2,4,5-tetrasubstituted and 2,4,5-trisubstituted imidazoles is achieved by condensation of 1,2-dicarbonyl compound, aldehyde, ammonium acetate and primary amine using antimony trichloride immobilized on silica gel (SiO2-OSbCl2) as a catalyst in ethanol at moderate temperature. Operational simplicity, practicability and applicability to various substrates make this method an interesting alternative to previously applied procedures. From the environmental standpoint, this eco-friendly green catalyst is stable, highly active, easy to prepare and handle.

Keywords

  • Heterogeneous catalyst,
  • Imidazoles,
  • Lewis acid,
  • SiO2-OSbCl2,
  • Sonication.
PDF HTML