Synthesis of 4,4´-(Arylmethylene)bis(1H-pyrazol-5-ols) catalyzed by nanosilica supported perchloric acid in water

  1. Department of Chemistry, Central Tehran Branch, Islamic Azad University, Tehran, Iran
  2. Department of Chemistry, Yazd Branch, Islamic Azad University, P.O. Box 89195-155, Yazd, Iran.

Published in Issue 2024-02-03

How to Cite

Sadeghi, B., & Ghorbani Rad, M. (2024). Synthesis of 4,4´-(Arylmethylene)bis(1H-pyrazol-5-ols) catalyzed by nanosilica supported perchloric acid in water. Iranian Journal of Catalysis, 4(2). https://oiccpress.com/ijc/article/view/3792

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Abstract

Reaction between aromatic aldehydes and 3âmethyl-1-phenyl-2-pyrazoline-5-one catalyzed by nano-SiO2/HClO4 in water under reflux provided a simple and efficient route for the synthesis of 4-((5-hydroxy-3-methyl-1-phenyl-1H-pyrazol-4-yl)(aryl)methyl)-3-methyl-1-phenyl-1H-pyrazol-5-ol derivatives in high yields.

Keywords

  • 3–Methyl-1-phenyl-2-pyrazoline-5-one,
  • Aromatic aldehydes,
  • Nano-SiO2/HClO4,
  • Water