Melamine trisulfonic acid (MTSA) as an efficient catalyst for the synthesis of triazolo[1,2-a]indazole-triones and some 2H-indazolo[2,1-b]phthalazine-triones

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  • Ardeshir Khazaei1,
  • Mohammad Ali Zolfigol2,
  • Toktam Faal Rastegar1,
  • Gholamabbas Chehardoli3,
  • Shadpour Mallakpour4,
  1. Faculty of Chemistry, University of Bu-Ali Sina, 65178, Hamedan, Iran.
  2. Department of Organic Chemistry, Faculty of Chemistry, Bu-Ali Sina University, Hamedan 6517838683, Iran.
  3. School of Pharmacy, University of Medical Sciences, Hamedan 65178, Iran.
  4. Nanotechnology and Advanced Materials Institute, Isfahan University of Technology, Isfahan, Iran.

Published in Issue 2024-02-03

How to Cite

Khazaei, A., Zolfigol, M. A., Faal Rastegar, T., Chehardoli, G., & Mallakpour, S. (2024). Melamine trisulfonic acid (MTSA) as an efficient catalyst for the synthesis of triazolo[1,2-a]indazole-triones and some 2H-indazolo[2,1-b]phthalazine-triones. Iranian Journal of Catalysis, 3(4). https://oiccpress.com/ijc/article/view/3776

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Abstract

Melamine trisulfonic acid (MTSA) as an efficient heterogeneous catalyst has been used for the one-pot preparation of triazolo[1,2-a]indazole-1,3,8-trione and 2H-indazolo[2,1-b]phthalazine-1,6,11-trione derivatives by the three-component condensation reaction of urazoles or phthalhydrazide, dimedone or 1,3-cyclohexanedione, and aldehydes under solvent-free conditions in good to excellent yields and short reaction times.

Keywords

  • 1. 3-cyclohexanedione,
  • Aldehyde,
  • Dimedone,
  • Melamine trisulfonic acid (MTSA),
  • Multi-component reaction,
  • Urazole
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