Study of an in situ carbocationic system formed from trityl chloride (Ph3CCl) as an efficient organocatalyst for the condensation of dimedone with arylaldehydes

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  • Abdolkarim Zare1,
  • Maria Merajoddin2,
  • Mohammad Ali Zolfigol3,
  1. Department of Chemistry, Payame Noor University, PO Box 19395-3697, Tehran, Iran
  2. Department of Chemistry, Payame Noor University, Iran.
  3. Department of Organic Chemistry, Faculty of Chemistry, Bu-Ali Sina University, Hamedan 6517838683, Iran.

Published in Issue 2024-02-03

How to Cite

Zare, A., Merajoddin, M., & Zolfigol, M. A. (2024). Study of an in situ carbocationic system formed from trityl chloride (Ph3CCl) as an efficient organocatalyst for the condensation of dimedone with arylaldehydes. Iranian Journal of Catalysis, 3(2). https://oiccpress.com/ijc/article/view/3759

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Abstract

Organocatalyst trityl chloride (Ph3CCl), by in situ formation of trityl carbocation with inherent instability, efficiently catalyzes the condensation of dimedone (5,5-dimethyl-1,3-cyclohexanedione) (2 equiv.) with arylaldehydes (1 equiv.) under solvent-free conditions to afford 9-aryl-1,8-dioxo-octahydroxanthenes in high to excellent yields and in relatively short reaction times. Formation of the carbocationic system is confirmed by studying IR, 1H NMR and UV spectra according to the literature. Moreover, a plausible mechanism based on the literature and observations is proposed for the reaction.

Keywords

  • 5-dimethyl-1. 3-cyclohexanedione),
  • Arylaldehyde,
  • Dimedone (5,
  • Organocatalyst,
  • Trityl carbocation,
  • Trityl chloride (Ph3CCl)
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