1,3-Dibromo-5,5-dimethylhydantoin (DBH) as a cheap and efficient catalyst for the synthesis of polyhydroquinolines and 12-aryl-8,9,10,12-tetrahydro [a] xanthene-11-ones

  1. Department of Chemistry, College of Science, University of Guilan, Rasht, Iran
  2. Department of Chemistry, College of Science, University of Mohaghegh Ardabili, Ardabil, Iran.
  3. Department of Chemistry, College of Science, University of Guilan, Rasht, zip code 41335, I.R. Iran.

Published in Issue 2024-02-03

How to Cite

Shirini, F., Imanzadeh, G. H., Abedini, M., & Ghods Ghasemabadi, P. (2024). 1,3-Dibromo-5,5-dimethylhydantoin (DBH) as a cheap and efficient catalyst for the synthesis of polyhydroquinolines and 12-aryl-8,9,10,12-tetrahydro [a] xanthene-11-ones. Iranian Journal of Catalysis, 3(2). https://oiccpress.com/ijc/article/view/3755

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Abstract

1,3-Dibromo-5,5-dimethylhydantoin (DBH), as a cheap and commercially available reagent, is efficiently able to catalyze the synthesis of polyhydroquinoline derivatives and 12-aryl-8,9,10,12-tetrahydro[a] xanthene-11-ones via one-pot multi-component reactions. This novel synthetic method has the advantages of low cost and availability of the catalyst, short reaction times, high to excellent yields, simple and easy work-up and purification of the products compared to the conventional methods reported in the literature.

Keywords

  • 3-Dibromo-5,
  • 5-dimethylhydantoin,
  • Aldehydes. 12-Aryl-8,
  • Multi-component reactions