Synthesis of 4,4â²-(arylmethylene)bis(1H-pyrazol-5-ols) via multi-component reactions by using silica-bonded sulfamic acid derivatives

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  • Shekoofeh Tayebi1,
  • Khodabakhsh Niknam2,
  1. Young Researchers Club, Gachsaran Branch, Islamic Azad University, Gachsaran, Iran.
  2. Department of Chemistry, Faculty of Sciences, Persian Gulf University, Bushehr 75169, Iran.

Published in Issue 2024-02-03

How to Cite

Tayebi, S., & Niknam, K. (2024). Synthesis of 4,4′-(arylmethylene)bis(1H-pyrazol-5-ols) via multi-component reactions by using silica-bonded sulfamic acid derivatives. Iranian Journal of Catalysis, 2(2). https://oiccpress.com/ijc/article/view/3725

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Abstract

The one-pot, multi-component synthesis of 4,4â²-(arylmethylene)bis(1H-pyrazol-5-ols) by tandem Knoevenagel-Michael reaction of phenylhydrazine, ethyl acetoacetate and aldehydes in the presence of silica-bonded N-propylpiperazine sulfamic acid (SBPPSA) as a recyclable solid acid catalyst was reported. SBPPSA showed much the same efficiency when used in consecutive reaction runs.

Keywords

  • Aldehydes,
  • 4′-(Arylmethylene)bis(1H-pyrazol-5-ols). Multi-component reactions,
  • Catalyst,
  • Silica-bonded N-propylpiperazine sulfamic acid,
  • 4
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