Nano-SiO2/hexamethylenetetramine promoted synthesis of pyrano[2,3-c] pyrazoles under solvent-free conditions

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  • Bi Bi Fatemeh Mirjalili*1,
  • Mina Keihanfar2,
  1. Department of Chemistry, College of Science, Yazd University, Yazd, P.O. Box 89195-741, Iran
  2. Department of Chemistry, Faculty of Sciences, Yazd University, P.O. Box 89195-741, Yazd, I.R. Iran.

Published in Issue 2024-02-03

How to Cite

Mirjalili, B. B. F., & Keihanfar, M. (2024). Nano-SiO2/hexamethylenetetramine promoted synthesis of pyrano[2,3-c] pyrazoles under solvent-free conditions. Iranian Journal of Catalysis, 10(1). https://oiccpress.com/ijc/article/view/3539

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Abstract

In this study, the nano-SiO2/hexamethylenetetramine as a new basic heterogeneous nanocatalyst was prepared and used for the synthesis of pyranopyrazole via the four-component reaction. Various aldehydes, hydrazine hydrate, ethyl acetoacetate and malononitrile were reacted at room temperature under solvent-free and grinding conditions. The morphology and structure of nano-catalyst were investigated by techniques such as FT-IR spectroscopy, FESEM, TEM, XRD, CHNS elemental analyzer and TGA. The structure of pyranopyrazoles was determined by spectroscopic data of FTIR and NMR. The principal affairs of this procedure are easy work-up, high yields, mild conditions and short reaction times.

Keywords

  • 3-c]pyrazole,
  • Basic nanocatalyst,
  • Multicomponent reactions,
  • Nano-SiO2/hexamethylenetetramine,
  • Pyrano[2,
  • Reusable catalyst.
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