Nanocrystalline TiO2 as an efficient and reusable catalyst for the one-pot synthesis of polyhydroquinolien derivatives via Hantzsch reaction

PDF HTML
  • Farhad Shirini1,
  • Seyyed Vahid Atghia2,
  • Meysam Alipour Khoshdel3,
  1. Department of Chemistry, College of Science, University of Guilan, Rasht, Iran
  2. Department of Chemistry, College of Science, University of Guilan, Rasht, I.R. Iran.
  3. Department of Chemistry, College of Science, University of Guilan, Rasht, zip code 41335, I.R. Iran.

Published in Issue 2024-02-03

How to Cite

Shirini, F., Atghia, S. V., & Alipour Khoshdel, M. (2024). Nanocrystalline TiO2 as an efficient and reusable catalyst for the one-pot synthesis of polyhydroquinolien derivatives via Hantzsch reaction. Iranian Journal of Catalysis, 1(2). https://oiccpress.com/ijc/article/view/3536

PDF views: 169

HTML views: 14

Abstract

An efficient synthesis of polyhydroquinoline derivatives was reported via four-component coupling reactions of aldehydes, 1,3-dicarbonyl ketones (dimedone or 1,3-cyclohexanedione), ethyl acetoacetate or methyl acetoacetate and ammonium acetate in the presence of a catalytic amount of nanocrystalline TiO2 under solvent free conditions. The reported method is mild, rapid and has the advantages such as heterogeneous catalysis, simple work-up procedure, recyclability of the catalyst and purification of products without chromatographic methods.

Keywords

  • Hantzsch reaction.,
  • Heterogeneous catalysis,
  • Nanocrystalline TiO2,
  • one-pot condensation reaction.,
  • Polyhydorquinolie derivatives
PDF HTML